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Assignment: Case Studies

Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.

For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.

Resources

Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.

WEEKLY RESOURCES

To Prepare:

Review the case study posted in “Announcements” by your Instructor for this Assignment
Review the information provided and answer questions posed in the case study
When recommending a medication, write out a complete prescription for the medication
Whenever possible, use clinical practice guidelines in developing your answers when possible
Include at least three references to support your answer and cite them in APA format.
By Day 7 of Week 7
Submit the Assignment.

submission information
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To submit your completed assignment, save your Assignment as WK7Assgn_LastName_Firstinitial
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Next, click on Upload File and select Submit Assignment for review.

case study
WEEK 7: Musculoskeletal System

Class,

Welcome to week 7! This week we will apply pharmacology concepts to musculoskeletal system disorders. We will cover the topics of NSAIDs, DMARDs, opioids, and muscles relaxants in relation to the treatment of arthritis, RA, gout, and addiction.

When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.

WEEK 7 ASSIGNMENT (covers weeks 7 & 8)

Submit your Assignment by Day 7 of Week 7 (Sunday night, 11:59 pm ET).

Case studies are a useful way for you to apply your knowledge of pharmacokinetic and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.

For your week 7 assignment, evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.

Directions: For each of the scenarios below, answer the questions using your required learning resources, Medscape, and clinical practice guidelines (ie AHA, ACC, ADA, GINA). When recommending medications, write out a complete prescription for each medication. What order would you send to a pharmacy? Include drug, dose, route, frequency, # dispensed (days supply), refills, special instructions etc. Also state if you would continue, discontinue or taper the patient’s current medications (if applicable). Use at least 3 sources for each scenario and cite sources using APA format. LIST REFERENCES AFTER EACH SCENARIO.

SCENARIO 1

What are the errors in the following prescriptions (1 per prescription)? Rewrite each prescription correctly. What is each medication’s classification and mechanism of action (MOA)?

fentanyl transdermal patch 12 mcg/hr Apply 1 patch to skin every 72 hours #10 patches 1 RF
Skyrizi 600 mg/10 mL IV infused over 1 hour at weeks 0, 4, 8 and 12 for Crohn’s disease #1 vial 3 RF
allopurinol 300 mg PO QID #120 0 RF
adalimumab (Humira) 120 mg SQ inject every other week #2 syringes 1 RF
bupropion XL 150 mg PO BID for smoking cessation #60 1 RF
SCENARIO 2

Zolpidem has a half-life of 3 hours. If a patient takes 10 mg at 21:00, what will the blood level be at 06:00? Name 3 antidepressants/antipsychotics you might prescribe for patients with co-existing depression and insomnia. What is their MOA? Include complete medication orders and patient monitoring for each of the 3 medications.

SCENARIO 3

Match the following patients to the most appropriate antidepressant for their symptom cluster. Each medication option is used once. Include MOA, medication side effects, and a medication order for at least 1 of the patients.

Patient Presentation

1 fibromyalgia, insomnia, no depression

2 diabetic neuropathy, fatigue, depression

3 postherpetic neuralgia, poor appetite, insomnia

4 chronic musculoskeletal pain, anxiety, hot flashes

5 fibromyalgia, no mood disorder, prefers non-sedating

Medication options:

amitriptyline
duloxetine
mirtazapine
venlafaxine
milnacipran
SCENARIO 4

OH is an 9-year-old male brought in by his father due to concerns about behavior and school performance. His teacher reports that OH is frequently out of his seat, talks excessively, blurts out answers, and has difficulty completing tasks and following directions. At home, he often loses homework, seems forgetful, and struggles to stay focused on activities like reading. Growth and development are age-appropriate. He sleeps about 9 hours per night but still wakes up feeling tired. There are no signs of anxiety, depression, or other mood disorders. What is the most likely diagnosis? What is an appropriate first-line medication (include complete medication order)? What monitoring parameters should be considered during treatment?

Note on Assignment Attempts

Students are expected to review their work and submissions of work carefully prior to due dates. Unless otherwise approved by the faculty, students are allowed one submission of graded work per assignment. While the classroom allows for multiple submissions, once an assignment is graded, submissions will no longer be accepted unless approved by the faculty. If an assignment is submitted prior to the assignment deadline and has not yet been graded, then students may submit a revised assignment prior to the assignment deadline. Once the deadline has passed, resubmission is not permitted.

Late Assignment Policy

Students are expected to submit assignments by the due dates noted in the course and welcome announcement. In extenuating circumstances, such as illness, the student must contact the instructor as soon as possible to discuss the situation. In those circumstances, faculty will determine the appropriate course of action for the student. Depending on the situation, these actions may include recommendations to drop the course (if within the university drop/withdrawal period), acceptance of some or all of the overdue assignments with or without penalties, or failure to accept assignments.

Assignments submitted late without the prior agreement of the instructor, outside of an emergency absence, or in violation of agreements for late submission, will receive a grade reduction for the assignment amounting up to 20%. Each day late will result in a 4% point deduction up to day 5. After 5 days, the assignment will be graded a zero.

However, ALL assignments, quizzes, and exams must be completed to pass the course.

Wishing you much success,