Assignment 4: Ethics Related to Research

PHYS 997 Special Topics B Assignment 4: Ethics Related to Research Instructions: – Make sure you label question number and sub part that you are answering (e.g. 2.B.1). – Concise answers preferred. – Submit through Moodle assignment 4 submission portal. Questions 1. Describe any two unethical historical human experiments that lead to the need for ethical guidelines in Human research (25 marks) 2. Summarise the main recommendations of the Belmont report under these headings. (You may directly paraphrase parts of the report but summarise each section). a. Boundaries Between Practice and Research (10 marks) b. Basic Ethical Principles (15 marks) i. Respect for Persons ii. Beneficence iii. Justice c. Applications (30 marks) i. Informed Consent ii. Assessment of Risk and Benefits iii. Selection of Subjects 3. Define the five different levels of evidence from level I,II, IIIa, IIIb and level IV and how they relate to clinical trials (Phase) as defined in Metcalfe et al 2007. Then name any one trial in each category that fits within each level of evidence and explain why it fits within that trial level of evidence (20 marks) Assignment set by: Dr. Joel Poder TOTAL MARKS = 100