An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. In 1-2 pages, you will answer the questions provided following the case scenario. You must use current evidence-based resources to support your answers. Follow APA guidelines. Follow the grading rubric.
To prepare:
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
The Assignment
Develop a 1- to 2-page case study analysis by answering the questions provided following the case scenario.
Include a title page, introduction, summary, and references.
Weekly references
- Rogers, J. (2023). McCance & Huether's pathophysiology (9th ed.). Elsevier – Evolve.
- Chapter 7: Innate Immunity: Inflammation and Wound Healing: Summary Review
- Chapter 8: Adaptive Immunity: Summary Review
- Chapter 9: Alterations in Immunity: Summary Review
- Chapter 10: Infection: Summary Review
- Chapter 11: Stress and Disease: Summary Review
- Chapter 12: Cancer Biology: Summary Review
- Chapter 13: Cancer Epidemiology: Summary Review
- Chapter 14: Cancer in Children Adolescent
- Chapter 46: Structure, Function and Disorders of the Integument
- Chapter 47: Alterations of the Integument in Children
NURS_6501_Week 2_Case Study_Assignment_Rubric
9/2/25, 9:51 AM Week 2: Assignment
https://waldenu.instructure.com/courses/184902/assignments/2577264?module_item_id=7767752 1/5
Criteria Ratings Pts
Develop a 1- to 2- page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis.
30 pts
What role do genetic mutations play in the development of the disease?
25 pts
30 to >27.0 pts Excellent The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.
27 to >24.0 pts Good The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response supported by evidence and/or research, as appropriate, to support the explanation.
24 to >22.0 pts Fair The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague or inaccurate. … The response is supported with explanations that are vague or based on inappropriate evidence/research.
22 to >0 pts Poor The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague and inaccurate, or the description is missing. … The response does not include rationales, or the explanations are vague or based on inappropriate or no evidence/research.
25 to >22.0 pts Excellent The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.
22 to >19.0 pts Good The response includes an accurate analysis of the genes that may be associated with the development of the disease.
19 to >17.0 pts Fair The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.
17 to >0 pts Poor The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing.
9/2/25, 9:51 AM Week 2: Assignment
https://waldenu.instructure.com/courses/184902/assignments/2577264?module_item_id=7767752 2/5
Criteria Ratings Pts
What is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease?
30 pts
Written Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well- developed ideas, flow logically, and demonstrate
5 pts
30 to >27.0 pts Excellent The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.
27 to >24.0 pts Good The response includes an accurate explanation of the impact of disease on the immune system.
24 to >17.0 pts Fair The response includes a vague or inaccurate explanation of the impact of disease on the immune system.
17 to >0 pts Poor The response includes a vague and inaccurate explanation of the impact of disease on the immune system.
5 to >4.0 pts Excellent Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … Content is supported by current evidence- based sources.
4 to >3.0 pts Good Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Some content is supported by current evidence- based sources.
3 to >2.0 pts Fair Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%– 79% of the time. … Some content is supported by current evidence- based sources.
2 to >0 pts Poor Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No content is supported by current evidence- based source.
9/2/25, 9:51 AM Week 2: Assignment
https://waldenu.instructure.com/courses/184902/assignments/2577264?module_item_id=7767752 3/5
Criteria Ratings Pts continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. Content is supported by current evidence- based sources.
Written Expression and Formatting – English Writing Standards: Correct grammar, mechanics, and proper punctuation 5 pts
Written Expression and Formatting – The paper follows correct APA format for title page, headings, font,
5 pts
5 to >4.0 pts Excellent Uses correct grammar, spelling, and punctuation with no errors.
4 to >3.0 pts Good Contains a few (1 or 2) grammar, spelling, and punctuation errors.
3 to >2.0 pts Fair Contains several (3 or 4) grammar, spelling, and punctuation errors.
2 to >0 pts Poor Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.
5 to >4.0 pts Excellent Uses correct APA format with no errors.
4 to >3.0 pts Good Contains a few (1 or 2) APA format errors.
3 to >2.0 pts Fair Contains several (3 or 4) APA format errors.
2 to >0 pts Poor Contains many (≥ 5) APA format errors.
9/2/25, 9:51 AM Week 2: Assignment
https://waldenu.instructure.com/courses/184902/assignments/2577264?module_item_id=7767752 4/5
Criteria Ratings Pts spacing, margins, indentations, page numbers, running heads, parenthetical/in- text citations, and reference list.
Total Points: 100
9/2/25, 9:51 AM Week 2: Assignment
https://waldenu.instructure.com/courses/184902/assignments/2577264?module_item_id=7767752 5/5