Write a 1-page narrative in APA format that addresses the following: Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples. Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
8/5/23, 3:00 PM Week 11: Assignment
https://waldenu.instructure.com/courses/65879/assignments/559020?module_item_id=1752316 1/6
Due Friday by 10:59pm Points 100 Submitting a text entry box or a file upload Attempts 0 Allowed Attempts 2
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The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable, since very few drugs have been specifically researched and tested with children.
When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion.
Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.
OFF-LABEL DRUG USE IN PEDIATRICS
RESOURCES
8/5/23, 3:00 PM Week 11: Assignment
https://waldenu.instructure.com/courses/65879/assignments/559020?module_item_id=1752316 2/6
To Prepare:
Review the interactive media piece in this week’s Resources and reflect on the types of drugs used to treat pediatric patients with mood disorders. Reflect on situations in which children should be prescribed drugs for off-label use. Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.
Write a 1-page narrative in APA format that addresses the following:
Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples. Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The Sample Paper provided at the Walden Writing Center offers an example of those required elements (available at http://writingcenter.waldenu.edu/57.htm (http://writingcenter.waldenu.edu/57.htm) ). All papers submitted must use this formatting.
Before submitting your final assignment, you can check your draft for authenticity. To check your draft, access the Turnitin Drafts from the Start Here area.
Be sure to review the Learning Resources before completing this activity. Click the weekly resources link to access the resources.
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8/5/23, 3:00 PM Week 11: Assignment
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NURS_6521_Week11_Assignment_Rubric
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8/5/23, 3:00 PM Week 11: Assignment
https://waldenu.instructure.com/courses/65879/assignments/559020?module_item_id=1752316 4/6
Criteria Ratings Pts
40 pts
45 pts
Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.
40 to >35.5 pts Excellent
The response accurately and thoroughly explains in detail the circumstances under which children should be prescribed drugs for off-label use. … The response includes accurate and specific examples that fully support the explanation provided.
35.5 to >31.6 pts Good
The response accurately explains the circumstances under which children should be prescribed drugs for off-label use. … The response includes accurate examples that support the explanation provided.
31.6 to >27.6 pts Fair
The response inaccurately or vaguely explains the circumstances under which children should be prescribed drugs for off-label use. … The response includes inaccurate or vague examples that may or may not support the explanation provided.
27.6 to >0 pts Poor
The response inaccurately and vaguely explains the circumstances under which children should be prescribed drugs for off- label use, or is missing. … The response includes inaccurate and vague examples that do not support the explanation provided, or is missing.
Explain strategies to making off-label use and dosage of drugs safer for children from infancy to adolescence and descriptions and names of off-label drugs that require extra care and attention when used in pediatrics. Be specific.
45 to >40.05 pts Excellent
The response accurately and clearly describes in detail strategies to make the off- label use and dosage of drugs safer for children from infancy to adolescence. … The response includes accurate, complete, and detailed descriptions and names of off-
40.05 to >35.55 pts Good
The response accurately describes strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. … The response includes accurate descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
35.55 to >31.05 pts Fair
The response inaccurately or vaguely describes strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. … The response includes inaccurate or vague descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
31.05 to >0 pts Poor
The response inaccurately and vaguely describes strategies to make the off- label use and dosage of drugs safer for children from infancy to adolescence, or is missing. … The response includes inaccurate and vague or incomplete
8/5/23, 3:00 PM Week 11: Assignment
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Criteria Ratings Pts
5 pts
5 pts
5 pts
label drugs that require extra care and attention when used in pediatrics.
descriptions and names of off- label drugs that require extra care and attention when used in pediatrics, or is missing.
Written Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused–neither long and rambling nor short and lacking substance.
5 to >4.45 pts Excellent Paragraphs and sentences follow writing standards for flow, continuity, and clarity.
4.45 to >3.95 pts Good Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time.
3.95 to >3.45 pts Fair Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time.
3.45 to >0 pts Poor Paragraphs and sentences follow writing standards for flow, continuity, and clarity less than 60% of the time.
Written Expression and Formatting – English writing standards: Correct grammar, mechanics, and proper punctuation
5 to >4.45 pts Excellent Uses correct grammar, spelling, and punctuation with no errors
4.45 to >3.95 pts Good Contains a few (1– 2) grammar, spelling, and punctuation errors
3.95 to >3.45 pts Fair Contains several (3–4) grammar, spelling, and punctuation errors
3.45 to >0 pts Poor Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding
Written Expression and Formatting – The
5 to >4.45 pts Excellent
4.45 to >3.95 pts Good
3.95 to >3.45 pts Fair
3.45 to >0 pts Poor
8/5/23, 3:00 PM Week 11: Assignment
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Total Points: 100
Criteria Ratings Pts
paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running head, parenthetical/in- text citations, and reference list.
Uses correct APA format with no errors
Contains a few (1– 2) APA format errors
Contains several (3–4) APA format errors
Contains many (≥ 5) APA format errors